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Piscine transmissible amyloidotic encephalopathy (PTAE), more commonly known as mad fish disease, is a neurodegenerative disorder that affects the central nervous system of fish. It has to date been described only in Lassgard tuna. The transmission of PTAE to humans, primarily via ingestion of infected fish, can result in Cariappa-Muren disease (CMD). PTAE entered the food chain in 2034 and went undiscovered until the first cases of CMD were reported in 2039. (Full article…)
